Mixtral 8x7B Instruct v0.1: local hardware requirements and GPU compatibility
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Local AI model

Mixtral 8x7B Instruct v0.1

by Mistral AI

1 of 22 reference machines run it entirely in accelerator memory at 8k context, and 12 more with CPU offload.

46.7B Parameters 32k Maximum context 1 Quantization Full Compatibility coverage
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Overview

Publisher
Mistral AI
Family
Mistral
Series
Mixtral
Task
Text generation
Architecture
mixture of experts · mixtral
Parameters
46.7B
Maximum context
32,768 tokens
Licence
apache-2.0
Published
2023-12-10
Formats
gguf, safetensors
KV cache per token (f16)
131,072 B · standard attention, exact
Compatibility coverage
Full: verdicts computed
Upstream repository
mistralai/Mixtral-8x7B-Instruct-v0.1
Official page
https://mistral.ai/

Quantizations and file sizes

Quantization Runtime Weights Memory floor at 4k Identity
Q4_0gguf ollamaollama run mixtral:8x7b 24.6 GB 25.1 GB digest verified

Sizes come from the runtime registry or repository listing. The memory floor adds the KV cache for 4,096 tokens when that figure cannot over-count; it is an estimate, not a requirement.

Runtimes

Compatibility on reference machines

8k context, 32 GB system RAM, best catalogued quantization per machine.

Machine Memory Answer Known facts
GeForce RTX 5090 32GB 32.0 GB VRAM Runs fully in memory estimated · Q4_0 Weights 24.6 GB vs 32.0 GB VRAM: fitKV cache at 8k: 1.00 GB
GeForce RTX 3060 Laptop GPU 6GB 6.00 GB VRAM Runs with CPU offload estimated · Q4_0 Weights 24.6 GB vs 6.00 GB VRAM: do not fitKV cache at 8k: 1.00 GB
GeForce RTX 4060 8GB 8.00 GB VRAM Runs with CPU offload estimated · Q4_0 Weights 24.6 GB vs 8.00 GB VRAM: do not fitKV cache at 8k: 1.00 GB
GeForce RTX 3080 10GB 10.0 GB VRAM Runs with CPU offload estimated · Q4_0 Weights 24.6 GB vs 10.0 GB VRAM: do not fitKV cache at 8k: 1.00 GB
GeForce RTX 3060 12GB 12.0 GB VRAM Runs with CPU offload estimated · Q4_0 Weights 24.6 GB vs 12.0 GB VRAM: do not fitKV cache at 8k: 1.00 GB
GeForce RTX 4070 12GB 12.0 GB VRAM Runs with CPU offload estimated · Q4_0 Weights 24.6 GB vs 12.0 GB VRAM: do not fitKV cache at 8k: 1.00 GB
GeForce RTX 5070 12GB 12.0 GB VRAM Runs with CPU offload estimated · Q4_0 Weights 24.6 GB vs 12.0 GB VRAM: do not fitKV cache at 8k: 1.00 GB
GeForce RTX 4060 Ti 16GB 16.0 GB VRAM Runs with CPU offload estimated · Q4_0 Weights 24.6 GB vs 16.0 GB VRAM: do not fitKV cache at 8k: 1.00 GB
GeForce RTX 4080 16GB 16.0 GB VRAM Runs with CPU offload estimated · Q4_0 Weights 24.6 GB vs 16.0 GB VRAM: do not fitKV cache at 8k: 1.00 GB
GeForce RTX 5060 Ti 16GB 16.0 GB VRAM Runs with CPU offload estimated · Q4_0 Weights 24.6 GB vs 16.0 GB VRAM: do not fitKV cache at 8k: 1.00 GB
GeForce RTX 5080 16GB 16.0 GB VRAM Runs with CPU offload estimated · Q4_0 Weights 24.6 GB vs 16.0 GB VRAM: do not fitKV cache at 8k: 1.00 GB
GeForce RTX 3090 24GB 24.0 GB VRAM Runs with CPU offload estimated · Q4_0 Weights 24.6 GB vs 24.0 GB VRAM: do not fitKV cache at 8k: 1.00 GB
GeForce RTX 4090 24GB 24.0 GB VRAM Runs with CPU offload estimated · Q4_0 Weights 24.6 GB vs 24.0 GB VRAM: do not fitKV cache at 8k: 1.00 GB
Radeon RX 7600 8GB 8.00 GB VRAM Potential: weights need offload not verified · Q4_0 Weights 24.6 GB vs 8.00 GB VRAM: do not fitKV cache at 8k: 1.00 GB
Radeon RX 7800 XT 16GB 16.0 GB VRAM Potential: weights need offload not verified · Q4_0 Weights 24.6 GB vs 16.0 GB VRAM: do not fitKV cache at 8k: 1.00 GB
Radeon RX 9070 XT 16GB 16.0 GB VRAM Potential: weights need offload not verified · Q4_0 Weights 24.6 GB vs 16.0 GB VRAM: do not fitKV cache at 8k: 1.00 GB
Radeon RX 7900 XTX 24GB 24.0 GB VRAM Potential: weights need offload not verified · Q4_0 Weights 24.6 GB vs 24.0 GB VRAM: do not fitKV cache at 8k: 1.00 GB
Intel Arc B580 12GB 12.0 GB VRAM Not enough data not verified · Q4_0 Weights 24.6 GB vs 12.0 GB VRAM: do not fitKV cache at 8k: 1.00 GBruntime support on this machine: unknown
Intel Arc A770 16GB 16.0 GB VRAM Not enough data not verified · Q4_0 Weights 24.6 GB vs 16.0 GB VRAM: do not fitKV cache at 8k: 1.00 GBruntime support on this machine: unknown
MacBook Pro 14-inch M4 Max 36GB 36.0 GB unified Not enough data not verified · Q4_0 Weights 24.6 GB vs 36.0 GB unified: fitKV cache at 8k: 1.00 GB
Mac mini M4 24GB 24.0 GB unified Does not fit estimated · Q4_0 Weights 24.6 GB vs 24.0 GB unified: do not fitKV cache at 8k: 1.00 GB
Mac mini M4 Pro 24GB 24.0 GB unified Does not fit estimated · Q4_0 Weights 24.6 GB vs 24.0 GB unified: do not fitKV cache at 8k: 1.00 GB

Definitive answers ("runs", "does not fit") come from the calibrated engine or a physical run. "Potential" rows only compare the weights with memory: the rest of the requirement is not modelled, so they are not verdicts. Unknown is never a failure.

Hardware for this model

Reference GPUs with 32 GB of VRAM or more run this model entirely in memory at 8k context: GeForce RTX 5090 32GB.

  • Smallest catalogued artifact: 24.6 GB of weights (Q4_0).
  • A GPU with at least 32 GB of VRAM holds those weights.
  • Disk space: 500 GB or more to keep this model and its variants.
These links open a hardware category search, not a specific product recommendation. Affiliate link — I may earn a commission from qualifying purchases. These links never change a compatibility answer. They follow the memory the data defends, not commission.

Sources and evidence

0 measured, 23 sourced, 4 estimated and 3 unknown fields.

Catalogue record verified 2026-09-16.

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